Each province、Autonomous Region、People's Government of Municipal Municipality，All Ministries and Commissions of the State Council、Direct institutions:

The national basic drug system is the basis of the drug supply guarantee system，It is an important content of basic public services in the medical and health field。Since the new round of medical reform，The establishment and implementation of the national basic drug system，System for the Supply of Medicine for Significant Drugs、Guarantee basic medication for the masses、Activating the burden of patients to play an important role。At the same time，There are also incomplete adaptation to the needs of basic clinical medication、Lack of incentive mechanisms、There is a gap between the quality and efficacy of imitation varieties and the quality of the original variety、Inadequate supply mechanisms and other problems。To implement the National Health and Health Conference、"Healthy China 2030" planning and deployment requirements for deepening the reform of the pharmaceutical and health system，Further improve the national basic drug system，Agree with the State Council，The following opinions are now proposed。

1. Overall requirements

Comprehensively implement the Party's 19th National Congress and 19th Middle School、The spirit of the Third Plenary Session，Guided by Xi Jinping's new era of socialism with Chinese characteristics，Adhere to people's health as the center，Strengthen basic drugs "Promoting Basic、Control must be necessary、Safe supply、Priority use、Guarantee quality、A functional positioning of reducing burden，Selection from basic drugs、Production、circulation、Use、Payment、Monitoring and other links to improve policy，Comprehensive driving the construction of the drug supply guarantee system，Strive to ensure the safety and effectiveness of drugs、Reasonable price、Full supply，Relieve the problem of "expensive medical treatment"。Promote the connection of medication for superior medical institutions，Helping the construction of a hierarchical diagnosis and treatment system，Promoting the transformation and upgrading of the pharmaceutical industry and supply -side structural reform。

2. Dynamic adjustment optimization directory

(1) Adapt to basic medical and health needs。Guided by meeting the needs of basic medication stake online sports bettingfor stake sports betting appthe prevention and treatment of the disease，According to my country's disease spectrum and medication characteristics，Fully consider the basic national conditions and guarantee capabilities at this stage，Adhere to science、Public、Fairness、The principle of fairness，Diagnosis and treatment specifications、Clinical diagnosis and treatment guidelines and expert consensus are based on，Chinese and Western Medicine and Western Medicine，Select the appropriate amount of basic drug varieties，Meeting common diseases、Chronic disease、Emergency rescue and other major clinical needs，Take care of special groups such as children and the needs of public health prevention and control。Strengthen evidence -based decision -making，Highlighting the clinical value of drugs; specifications of specifications，Being able to take oral muscles，Energy muscle injection without infusion。Support the development of traditional Chinese medicine，Encourage the research and development innovation of the pharmaceutical industry。

(2) Improve the management mechanism of the directory adjustment。Optimize the selection and adjustment of the basic drug directory，Comprehensive Drug Clinical Application Practice、Standard changes in drugs、New situation of drugs and other factors，Regular assessment of the basic drug directory、Dynamic adjustment，The adjustment cycle does not exceed 3 years in principle。New approval list、The efficacy is significantly improved and the price is reasonable compared to the available drugs，You can start the adjustment program in time。Persist in adjusting and reconflowing in parallel，Priority adjustment of validity and security evidence is clear、Pharmaceutical varieties with significant cost benefits; focus，More serious adverse reactions occurred、It should not be used as a basic drug for evaluation，and medicines with more risk -effective or better cost -effective varieties。In principle, no supplements are not added in various places，A small number of ethnic medicines can be added。

Three, effectively guarantee production and supply

(3) Improve effective supply capabilities。Take the implementation of the basic drug system as an important part of improving the pharmaceutical industry policy and industry development plan，Encourage enterprise technological progress and technological transformation，Promoting the production quality system that is in line with the international advanced level of enterprises，Enhance the capacity of basic drug production。Counter a survey of the status quo of production enterprises，For clinical necessity、Small dosage or low transaction price、Inadequate production power of the enterprise caused the basic drugs that are prone to shortage in the market，It can be built by the government，Determines a reasonable procurement price through market matching、fixed -point production、Unified distribution、Incident in reserves and other measures to ensure supply。

(4) Improve the purchase and distribution mechanism。Fully consider the special product attributes of the medicine，Give play to the role of the government and the market，Adhere to the centralized procurement direction，Implementation Stake Sports Bettingof stake online sports bettingdrug classification purchases，Guide to form a reasonable price。Do a good job in the use of medication for superior medical institutions，Promoting the purchase of public medical institutions in the city (county) domain，Promoting drug reduction price，Standard varieties of basic drug procurement、Dosage form、Specification，Meet the needs of the masses。Encourage specialist hospitals such as tumors to carry out cross -regional joint procurement。Production enterprises as the first responsible person to ensure basic drug supply and distribution，The contract should be fulfilled，Especially to ensure remote、Drug distribution in areas in areas of inconvenience in traffic。For the shortage of medication due to corporate reasons，Enterprises shall bear the liability for breach of contract，and in a timely manner from relevant departments and units into the dishonesty record。The medical insurance agency shall allocate medical insurance funds to the medical institution in a timely manner in accordance with the agreement。Medical institutions shall settle the payment in a timely manner in accordance with the contract;，Give notification criticism，or order to rectify the time limit。

(5) Strengthen the response to the shortage of shortages。Establish and improve the national shortage drug monitoring and early warning system，Strengthen drug research and development、Production、circulation、Use of polygon information collection，Accelerate the realization of direct reports of medical institutions at all levels，Tracking monitoring the source of pharmaceutical goods、Corporate inventory and market transaction behavior，Comprehensive research and judgment potential shortage factors and trends，Discover the shortage risk as soon as possible，Classification category for different shortages of shortage。Monopoly raw materials market and push high drug price lead to shortage of drugs，Suspecting the monopoly agreement and the abuse of market dominance，Carry out antitrust surveys in accordance with the law，Increased punishment。Incorporate the shortage of drugs required for the army into the national shortage drug emergency guarantee system，Through military -civilian integration method，Establishing a shortage of shortages need to coordinate the coordination and linkage mechanism of drugs and land，Guarantee forces urgently need shortage and emergency combat reserve medicinal materials。

Fourth, comprehensively equipped preferred use

(6) Strengthen the equipment use management。Adhere to the dominant position of basic drugs，Basic drug use management of strengthening medical institutions，In the province, the proportion of basic drugs in public medical institutions is clear，Continuously improve the use of basic drugs of medical institutions。Public medical institutions based on functional positioning and diagnosis and treatment，Reasonable equipped with basic drugs，Guarantee the needs of basic clinical medication。Pharmaceutical centralized procurement platform and medical institution information system should be marked with basic drugs，Reminder that medical institutions are prioritized、Doctors are preferred。Use the use of basic drugs My stake betting appas the key content of prescription review，Notice to the basic Stake Sports Bettingdrugs that are not preferred without justified reasons。To the doctor、Pharmacists and managers increase the basic drug system and basic drug clinical application guide、Prescription collection training strength，Improve the rational use and management level of basic drugs。Encourage other medical institutions to be equipped with basic drugs。

(7) Establish a priority incentive mechanism。Scientifically set indicators of basic drugs of clinical departments in medical institutions，Integrated into the assessment。The use of basic drugs with the implementation of subsidy funds for the basic drug system for the grassroots level。Deepen the reform of the medical insurance payment method，Establish and improve the "balance retaining for the medical insurance agency and the medical institution、Reasonable over -burden "incentives and risk sharing mechanisms。By formulating the method of pharmaceutical and medical insurance payment standards，Guide medical institutions and medical staff reasonable diagnosis and treatment、Reasonable medication。

(8) Implementing clinical use monitoring。Establish a sound country to rely on existing resources、Provincial two -level drug use monitoring platform and country、Provincial、Earth City、County 4 -level monitoring network system，Key monitoring of basic drugs of medical institutions、Use quantity、Procurement price、Supply distribution and other information，and whether the prescription medication meets the diagnosis and treatment specifications。Carry out comprehensive evaluation of drugs focusing on basic drugs，Guiding clinical safety and reasonable medication。Strengthen information interconnection between departments，Supply basic drugs from raw materials to production、circulation、Use、Price、Reimbursement and other dynamic monitoring of the whole process。

5. Reduce the burden of medication for the masses

(9) Gradually improve the actual guarantee level。Improve medical insurance payment policy，For therapeutic drugs in the basic drug directory，When the medical insurance department adjusts the medical insurance directory，Putting the qualified priority in the directory range or adjusting the classification of A and B according to the procedure。For the national immunization planning vaccine and anti -AIDS、Tuberculosis、Basic drugs stake online sports bettingfor the prevention and control of major public health such as parasitic disease，Increase government investment，Reduce the burden of medication for the masses。

(10) Explore the valid way to reduce the burden of patients。Encourage places to diagnose the basic drug system and graded、Family doctor signing service、Organic combination of chronic disease health management，At hypertension、Diabetes、In chronic disease management such as severe mental disorders，Basic drugs under the premise of ensuring the efficacy，Maximum reduction of patient cost expenses，Enhance the masses to get the sense of gain。

6. Improve quality and safety level

(11) Strengthen quality and safety supervision。Implement the full variety coverage of basic drugs，Join the results of sampling inspections to the society。Stake Sports BettingEncourage enterprises to evaluate after the drug listing。stake betting appStrengthen the monitoring of adverse reactions of basic drugs，Strengthening drug safety early warning and emergency response mechanism。Strengthen the supervision and inspection of basic drug production links，Supervise enterprises to produce compliance in accordance with the law，Guarantee quality。

(12) Promote the consistency evaluation of the quality and efficacy of generic drugs。Drug varieties that pass consistency evaluation，Catalog of the basic drug in priority according to the program。Makers that have been included in the basic drug directory，Stake Sports BettingEncourage enterprises to carry out consistency evaluation，Basic drug varieties that have not passed consistency evaluation，Gradually call the directory。Encourage medical institutions to prioritize and use consistency evaluation、A basically price of basic drugs。

Seven, strengthen organizational guarantee

(13) Strengthen organizational leadership。The implementation of the national basic drug system is the Party Central Committee、The important deployment made by the State Council in the field of health and health，Governments at all levels must implement leadership responsibilities、Safe liability、Management responsibility、Supervision responsibility，Incorporate the implementation of the national basic drug system into the government performance assessment system，Make sure to achieve practical results。Relevant departments must refine policy measures，Improve long -term mechanism，Strengthen collaboration and cooperation，Form work joint force。

(14) Strengthen supervision and evaluation。Establish and improve the basic drug system implementation supervision and evaluation system，Give full play to the role of third -party evaluation，Reinforcement results use，Policies related to the basic drug system in time according to the results of supervision and evaluation。Encourage places to combine the actual situation，Focus on ensuring basic drug supply and preferred use、Reduce the burden of the masses，Exploring effective practices and modes，Timely summarizing promotion。

(15) Strengthen publicity guidance。Through TV、Broadcast、Newspapers、Internet new media and other channels，Fully publicize the target positioning of the basic drug system、​​Important significance and policy measures。Properly respond to social concerns，Strengthen policy interpretation，Properly respond to social concerns，Reasonable guidance of social expectations，Create a good social atmosphere for the implementation of the basic drug system。