Novartis "Subi Fumen" Behind: Drug warning for failure
Release time: 2010-05-24 & nbsp & nbsp & nbsp Source:
As an agent lawyer of Li Lili's family，Anhui Tianlin Law Firm Cheng Lin has been at the beginning of the year，Plugs Beijing Nuohua Pharmaceutical Co., Ltd. (hereinafter referred to as "Novartis") to the People's Court of Changping District, Beijing，The reason for the prosecution to conceal the adverse reactions of Nuohua will cause the potential danger of death。
However, the 746,000 yuan claiming from Novartis may not be the focus of Novartis Anti -hepatitis B virus virus Dipbidin (the product name "Subi Fu") incident。Behind this ordinary medical dispute case，Because it involves 500 compulsory drug companies，Involved in the vital interests of the 130 million hepatitis B virus carriers，Involved in the contradiction between doctors and patients，attracted the attention My stake betting appof stake betting appmany parties。Hospital、Doctor、Pharmaceuticals、What responsibilities should the regulatory authority bear?
Anhui people Li Lili is taking Novartis Anti -hepatitis B virus drugs for Bibidding (the product name "Subi Fu") 1 year later，Delivery due to the dissolution of horizontal muscle。Hefei City Institute of Judicial Appraisal Science and Technology Research on Li Lili's death gives the final conclusion，Appraisal Opinions Digesting，Li Lili died in "Taking the muscle damage caused by" taking "Tabeidin"。
The case opened for the first time on March 9 this year，Previous，As the First Affiliated Hospital of Anhui Medical University for Li Lili，Method of mediation outside the court，Compensation Li Lili's family members 240,000 yuan。
After the case,，The focus of the media is first focused on Novartis as the Fortune 500 companies，Whether to let an immature product，Quickly passed the approval of the State Food and Drug Administration (SFDA) through some channels，Yesterday，SFDA display related documents issued by the First Financial Daily，The approval process of the front and rear approvals for 1 year，Not rumored by the outside world。
At the same time，Adverse reactions to the medicine，SFDA Adverse Reaction Center issued a warning on the peripheral neuropathy as early as April 2008.，To guide the doctor to properly use the plain ratio，and issued the "Notice on the Casserto of Two Films of Death Cases" on October 15th of that year。
Novartis told this reporter，SFDA after making the above measures，The company applied to the pharmaceutical regulatory department for a change in the drug supervision department in December of that year，stake betting appStake Sports Bettingand officially implemented the "upgrade" of the instructions in January 2009。
However, the most important reason for the above case is，Whether it is SFDA or these warnings from pharmaceutical companies，How much is the guidance significance in doctors? or，Is it meaningful?
Facts can also be seen，All local drug supervision bureaus also have cases reports。Zhejiang Food and Drug Administration, an internal file display on October 21, 2008，Including Ningbo Zongrui Hospital、PLA 113 Hospital、Jinhua City Central Hospital, all reports on the adverse reaction of Subi Fu。
Zhejiang Provincial Drug Administration also conveyed the information to the National Bureau and the Local Municipal Bureau。"I discovered these cases in the forum，Find Zhejiang Drug Administration。"Cheng Lin told reporters，"View related materials to Zhejiang Pharmaceutical Supervision Adverse Reactions in the form of a lawyer's letter，Not allowed。”
Facts，Not only Cheng Lin cannot obtain relevant information，This kind of information in Zhejiang Province has not formed an effective sharing mechanism in Anhui Province where Li Lili is located。The communication channels between drug supervision and hospitals are even more worrying。
A person who is engaged in drug registration management in multinational pharmaceutical companies tells this newspaper，Especially in the central and western regions，Information sharing between drug supervision and hospital、Delivery is very small，Doctors engaged in treatment of adverse reactions，"Sometimes it is very lagging，I don't even understand it at all。”
At the same time，Due to the expensive price of hepatitis B medication，After medication，Both Stake Sports Bettingstake betting appthe hospital and the doctor can get the benefits，The hidden rules of this industry have also led to some doctors to "ignore" warning information。
Cheng Lin also told this newspaper，It is so difficult to obtain relevant information as his lawyer，I can imagine that ordinary doctors are known。
One point that Nuohua, a multinational pharmaceutical company, is the point to report to reporters，Since the listing of Subi Fu，Its manual has been updated to the third version，The description of the adverse reaction description of the possibilities of Su Bi Fu is becoming more and more detailed、Easy to understand，Not only does it have a warning effect on doctors，It is also easy to understand for ordinary patients。
Previous，Novartis deliberately concealing the "adverse reaction" is the main reason for Cheng Lin's lawsuit，Cheng Lin thinks，Novartis "Sanyi Draft"，Before each change，There are related situations secret but not reported。
"After the drug is listed，During the medication process，The doctor will report to the company at any time，Supplement to make indications and adverse reactions，Therefore, it is normal for a few versions to change the manual。"Zhang Hongfei, a professor at the 39th Hospital of the Chinese People's Liberation Army, said this。
Where，In the company’s second edition manual，officially changed on January 4, 2009，Clearly added the content of the dissolving of horizontal muscle ?? "Muscle and Bone、connective tissue and bone tissue: Report for very rare transverse muscle dissolving "。
Unfortunately，This type of warning is compared to Li Lili's death，It must be a little late。
Yesterday，Zhang Hongfei My stake betting appstake online sports bettingtold reporters，I hope that this case can arouse the attention of all sectors of society for hepatitis B medication，Current，Unnecessary panic for medication and lack of prudent attitudes in the process of medical plan development，It is a warning of this case。"For example, everyone is familiar with the adverse reactions of penicillin，It can also be fatal，But it will not use it because of this，Instead, use drugs properly。”
However, the 746,000 yuan claiming from Novartis may not be the focus of Novartis Anti -hepatitis B virus virus Dipbidin (the product name "Subi Fu") incident。Behind this ordinary medical dispute case，Because it involves 500 compulsory drug companies，Involved in the vital interests of the 130 million hepatitis B virus carriers，Involved in the contradiction between doctors and patients，attracted the attention My stake betting appof stake betting appmany parties。Hospital、Doctor、Pharmaceuticals、What responsibilities should the regulatory authority bear?
Anhui people Li Lili is taking Novartis Anti -hepatitis B virus drugs for Bibidding (the product name "Subi Fu") 1 year later，Delivery due to the dissolution of horizontal muscle。Hefei City Institute of Judicial Appraisal Science and Technology Research on Li Lili's death gives the final conclusion，Appraisal Opinions Digesting，Li Lili died in "Taking the muscle damage caused by" taking "Tabeidin"。
The case opened for the first time on March 9 this year，Previous，As the First Affiliated Hospital of Anhui Medical University for Li Lili，Method of mediation outside the court，Compensation Li Lili's family members 240,000 yuan。
After the case,，The focus of the media is first focused on Novartis as the Fortune 500 companies，Whether to let an immature product，Quickly passed the approval of the State Food and Drug Administration (SFDA) through some channels，Yesterday，SFDA display related documents issued by the First Financial Daily，The approval process of the front and rear approvals for 1 year，Not rumored by the outside world。
At the same time，Adverse reactions to the medicine，SFDA Adverse Reaction Center issued a warning on the peripheral neuropathy as early as April 2008.，To guide the doctor to properly use the plain ratio，and issued the "Notice on the Casserto of Two Films of Death Cases" on October 15th of that year。
Novartis told this reporter，SFDA after making the above measures，The company applied to the pharmaceutical regulatory department for a change in the drug supervision department in December of that year，stake betting appStake Sports Bettingand officially implemented the "upgrade" of the instructions in January 2009。
However, the most important reason for the above case is，Whether it is SFDA or these warnings from pharmaceutical companies，How much is the guidance significance in doctors? or，Is it meaningful?
Facts can also be seen，All local drug supervision bureaus also have cases reports。Zhejiang Food and Drug Administration, an internal file display on October 21, 2008，Including Ningbo Zongrui Hospital、PLA 113 Hospital、Jinhua City Central Hospital, all reports on the adverse reaction of Subi Fu。
Zhejiang Provincial Drug Administration also conveyed the information to the National Bureau and the Local Municipal Bureau。"I discovered these cases in the forum，Find Zhejiang Drug Administration。"Cheng Lin told reporters，"View related materials to Zhejiang Pharmaceutical Supervision Adverse Reactions in the form of a lawyer's letter，Not allowed。”
Facts，Not only Cheng Lin cannot obtain relevant information，This kind of information in Zhejiang Province has not formed an effective sharing mechanism in Anhui Province where Li Lili is located。The communication channels between drug supervision and hospitals are even more worrying。
A person who is engaged in drug registration management in multinational pharmaceutical companies tells this newspaper，Especially in the central and western regions，Information sharing between drug supervision and hospital、Delivery is very small，Doctors engaged in treatment of adverse reactions，"Sometimes it is very lagging，I don't even understand it at all。”
At the same time，Due to the expensive price of hepatitis B medication，After medication，Both Stake Sports Bettingstake betting appthe hospital and the doctor can get the benefits，The hidden rules of this industry have also led to some doctors to "ignore" warning information。
Cheng Lin also told this newspaper，It is so difficult to obtain relevant information as his lawyer，I can imagine that ordinary doctors are known。
One point that Nuohua, a multinational pharmaceutical company, is the point to report to reporters，Since the listing of Subi Fu，Its manual has been updated to the third version，The description of the adverse reaction description of the possibilities of Su Bi Fu is becoming more and more detailed、Easy to understand，Not only does it have a warning effect on doctors，It is also easy to understand for ordinary patients。
Previous，Novartis deliberately concealing the "adverse reaction" is the main reason for Cheng Lin's lawsuit，Cheng Lin thinks，Novartis "Sanyi Draft"，Before each change，There are related situations secret but not reported。
"After the drug is listed，During the medication process，The doctor will report to the company at any time，Supplement to make indications and adverse reactions，Therefore, it is normal for a few versions to change the manual。"Zhang Hongfei, a professor at the 39th Hospital of the Chinese People's Liberation Army, said this。
Where，In the company’s second edition manual，officially changed on January 4, 2009，Clearly added the content of the dissolving of horizontal muscle ?? "Muscle and Bone、connective tissue and bone tissue: Report for very rare transverse muscle dissolving "。
Unfortunately，This type of warning is compared to Li Lili's death，It must be a little late。
Yesterday，Zhang Hongfei My stake betting appstake online sports bettingtold reporters，I hope that this case can arouse the attention of all sectors of society for hepatitis B medication，Current，Unnecessary panic for medication and lack of prudent attitudes in the process of medical plan development，It is a warning of this case。"For example, everyone is familiar with the adverse reactions of penicillin，It can also be fatal，But it will not use it because of this，Instead, use drugs properly。”
