The 2011 National Science and Technology Award of TCM Award Project Scan
Release time: 2012-02-21 & nbsp & nbsp & nbsp Source:
February 14，A good news from the 2011 National Science and Technology Reward Conference，13 TCM projects won the National Science and Technology Award。Among them, 1 item of the National Technology Invention Award、National Science and Technology Progress Award 12 items。Career development，Technology first，13 Chinese medicine projects won this award，Fully displayed the thick accumulation of traditional Chinese medicine、Filling and upward power，Showing Chinese medicine people for aggressiveness、The spiritual style of dare to innovate。Let's pay attention to these award -winning projects，Feel the strong pulse of the development of Chinese medicine technology。
Successful examples of modernization of Chinese patent medicine
The "Salviasis Polyphenolic acid and its powder needle" project that won the second prize of the National Technology Invention Award was jointly completed by the Shanghai Academy of Sciences Shanghai Pharmaceutical Institute and Shanghai Green Valley Pharmaceutical Co., Ltd.，Mainly complete people as Xuanli River、Wang Yiping、Xu Yaming, etc.。
Reasons for winning: from 1992，The clinical efficacy of the Chinese Academy of Sciences Shanghai Pharmaceutical Institute is unstable for the clinical efficacy of Danshen and its compound preparations、Adverse reactions often occur problems.，Discovering the water -soluble effective ingredients of Salva is mainly magnesium of Salviane and its homogeneous objects。Discovery through active screening and pharmacological research，Salva Magneste Pharmaceuticals The strongest effect。On the basis of this, it innovatively proposed the use of magnesium ginseng acetate as a quality control standard，Developed stir -up polyphenolic acid powder pins。Shanghai Drugs uses patented technology，Full of enrichment effective parts，Use fingerprint map technology at the same time，For medicinal materials、The quality of the raw drugs and preparations is comprehensively controlled，This ensures the efficiency of Salviac Polyphenol Acid Powder Plurgratous Products、Safety and quality stability、controllable。It overcomes the shortcomings of existing Danshen injection，It has important significance and value in clinical applications，It is an important result obtained by the modernization of traditional Chinese medicine in my country in recent years，Provides a successful example for the modernization of Chinese medicines。
Research on the Research on Molecular Mechanism of Authentic Medicine
The "Research and Application and Application and Application of Research and Application of the National Science and Technology Progress Award for Science and Technology Progress Award"、Institute of Medicinal and Plant Research, Chinese Academy of Medical Sciences、Shandong Analysis and Test Center、Tianjin University Complete。Mainly complete people Huang Luqi、Hu Shilin、Xiao Bagan, etc.。
Reasons for winning: This project takes "authentic formation = genetic mechanism+environmental mechanism" as the general outline，Choose more than ten types of real estate areas to be clear、Typical land medicinal materials commonly used in the community，Using phenotype characteristic mutations as the core，Use modern analysis technology、Molecular biology technology、Space Information Analysis Technology，and multiple statistics、Chemical measurement and other methods，Research authentic and non -land medicinal materials in chemical composition and content、Genetic background、Differences in environmental factor，and the correlation between the three; extract the characteristics of the surface of the ground medicinal material，Clarify its genetic and environmental mechanisms，Further comprehensive analytical scientific connotation，The theory of proposed the formation of local medicinal materials，and verify and apply through control experiments in combination with production practice。At the same time，Analysis of the intellectual property attributes of the medicinal materials，Putting the strategy of proposing the protection of the local medicinal materials。
Reveal the scientific utilization value of Chinese medicine resources
The stake betting appstake online sports betting"Establishment and Application of the Chinese Medicine Resources Chemistry Research System and its application" project that has won the second prize of the National Science and Technology Progress Award of Science and Technology "、Jiangsu Kangyuan Pharmaceutical Co., Ltd.、Jiangsu Provincial Institute of Traditional Chinese Medicine、Gansu Yigui Chinese Medicinal Material Technology Co., Ltd. Completed。Mainly complete people as Duan Jinyu、Xiao Wei、Qian Shihui, etc.。
Reasons for winning: Chinese medicine resource chemistry is a branch discipline for Chinese medicine resources，Based on traditional Chinese medicine resources with traditional medicinal effects and research objects，Based on the development and utilization of resources，Use natural product chemistry、Technology and methods of analyzing chemistry and efficacy evaluation，Reveal Chinese medicine resources (type、Class group) Multiple ways、Multi -layered scientific utilization value。This project follows the subject system and basic argument of natural resources，From the availability and multi -purpose departure of resources，Study the type of chemical composition in natural resources、Quality、Quantity、Time、Space and other basic attributes and their changes。Discussion on the research ideas and methods of the chemistry research of traditional Chinese medicine，Research system establishment and its application，and analyzed the research and comprehensive development and utilization research of Chinese medicine resources in the research instance
The status quo.
Forms a Chinese medicine clinical evidence -based evaluation mode
The clinical trial of the "Qi Shenyi Qi Di Pills for Condition of Myocardial infarction" by the second prize of the National Science and Technology Progress Award "、Chinese Academy of Traditional Chinese Medicine、Peking University First Hospital、Xiyuan Hospital of China Academy of Traditional Chinese Medicine、Tianjin Task Pharmaceutical Co., Ltd.。Mainly complete people as Zhang Boli、Shang Hongcai、Yao Chen, etc.。
Reasons for winning: This is a large -scale Chinese medicine with independent intellectual property rights、Multi -center random control clinical trial，Established and improved the research and evaluation mode of traditional Chinese medicine evidence -based research、Methods and key technologies，Established a randomization of the center、Data Management Electronic and other advanced methods and technology of large -scale clinical research platforms，Form a series of standard operation procedures，Is a example of traditional Chinese medicine evidence -based medical research。
This project is in 16 sub -centers nationwide、84 Chinese and Western Hospitals are carried out at the same time。After 5 years of hard work，A total of 3508 cases of qualified cases，Average follow -up 37. January，Data analysis results indicate，The incidence of the test group and the control group at the complex end event rate、The incidence of cardiovascular death incidence、Non -Deathful Reconstruction Instation Rate、There is no statistical difference between the incidence of non -dead strokes in the incidence of stroke，Reminder that Qi Shen Yilian Pills and Aspirin are equivalent to myocardial infarction secondary prevention effects;、Seattle's Angina pectoris meter and other minor efficiency indicators have no statistical differences in both groups，Reminder that Qi Shen Yishi Pills and enteric Avelin are equivalent to the quality of life after improving myocardial infarction，and compared with the enterico aspirin，Qi Yinyi Drip Pill Safety is particularly good。
Improve the competitiveness of the participation industry in my country
The second prize of the National Science and Technology Progress Award "New Variety Selection and Standardized Cultivation and Series Product Development" project is by Jilin Agricultural University、Institute of Specialty Research Institute of the Chinese Academy of Agricultural Sciences、Correction Pharmaceutical Group、Jilin Aodong Pharmaceutical Group Co., Ltd. completed。Mainly complete people Zhang Lianxue、Yang Limin、Feng family, etc.。
Reasons for winning: This project is divided into people to participate in standardized planting、Analysis of Ginseng Gene sequence and function analysis、Establishment of Ginseng Quality Standards and Fingerprints、Ginseng extraction technology and basic research of drugs、Topics such as the development of people's ginseng -related products。This project gives full play to the advantages of multi -disciplinary joint research，Focus on building basic research -application research -base construction -new drug research and development of innovative value chain，Get a series of innovative results，improved the quality and output of ginseng in my country，Promoting the competitiveness of the ginseng industry。
Reduce the medical cost of the intervertebral disk degeneration disease
The "Basic Research and Clinical Application of Basic Research and Clinical Application for the Treatment of Intervertebral Stake Sports BettingDisposity Diseases for the Treatment of Intervertebral stake sports betting appDisposter Diseases" project of the second prize of the National Science and Technology Progress Award. "、Shanghai Huangpu District Central Hospital、Shanghai Hyundai Chinese Medicine Co., Ltd. completed。Mainly complete people for Wang Yongjun、Shi Qi、Shiyangshan, etc.。
Reasons for winning: This project has made major breakthroughs in the technical and efficacy mechanism of traditional Chinese medicine for the treatment of cervical and lumbar spondylus disease，Form three innovative points。First, the principle of clinical guidance of "reconciling qi and blood" was formed，Established a "disease syndrome combination、Tyromics Theory "Clinical Standardization Plan。Second, the biological research platform of cervical lumbar spondylosis mode was established，revealed the early intervertebral disconnection、Middle、Late "Three changes" rules，clarifying the efficacy mechanism of the delay of the delay of the intervertebral disc.。Third, it formed "Plate source neck and low back pain"、"vertebrae osteophytes are derived from cartilage end board"、Original academic insights such as "Restoration of Spinal Balance" and the role of the role of nourishing qi and stasis。Achievements are widely promoted at home and abroad，reduced medical costs，Reflecting the value of Chinese medicine in the international academic circles。
Metabolic syndrome overall treatment effect is good
The "Chinese Medicine Cognition and Overall Treatment" project of the second prize of the National Science and Technology Progress Award of Science and Technology Progress Award is the Guang'anmen Hospital of the Chinese Academy of Chinese Medical Sciences、Tianjin Tashem Group Co., Ltd. completed。Mainly complete people as Xiaolin、Lian Fengmei、Zhu Yonghong, etc.。
Reasons for winning: This study lasted more than ten years，The first system proposes the theory of the ointment of metabolic syndrome (MS)，Filled the cause of Chinese medicine to MS、Pathopathery、Certificate of Certificate of Certificate, etc., created a mathematical model of the "Nei Jing" type 3 obesity，Provides new ways for MS's risk forecast。MS series governance method was established under the guidance of the theory of turbidity，Based on the Big Huanghuanglian Xiexin Decoction, a series of squares，The first clinical study of Chinese medicine intervention MS is carried out; confirmed that simple Chinese medicine compound treatment of different components MS，Can significantly reduce weight、Reduce waist circumference，Reduce blood glucose、Blood pressure，Improve insulin resistance, etc.，It has an overall treatment effect; compares with similar research with domestic and foreign homes，Breakthroughs in clinical efficacy; the main line with improving insulin resistance，From multiple ways，Explained the scientific connotation of the overall treatment of MS for Chinese medicine compound。Research results have been included in the relevant industry standards and national standard drafts。Relevant prescriptions are applied at more than 80 hospitals at home and abroad，Its theory is in Canada、South Africa、Japan、India and other more than 10 countries have been recognized，Training more than 500 specialists，Cumulative economic benefits of more than 100 million yuan。
The advantages of the prevention and treatment of traditional Chinese medicine are obvious
The "Chinese Medicine Lianhua Qing Plague Research" project, which won the second prize of the National Science and Technology Progress Award, was based on Shijiazhuang Yiling Pharmaceutical Co., Ltd.、Beijing You'an Hospital Affiliated to Capital Medical University Completed。Mainly complete people for Jia Zhenhua、Wu Yiling、Guo Shuanggeng, etc.。
Reasons for winning: This study is a more mature and complete Chinese medicine application research。First use the concept of the vein space position of the "three -dimensional stereo network system" in China in China，Discuss the characteristics of the pathogenesis of external temperature and fever and plague from Yangluo to the meridian stage, and the transmission law that is easy to pass into the internal organs and yin，Put forward the "active intervention" treatment concept:，Double solution in the table;，Tripping the disease; overall adjustment，Multi -target treatment，Develop "Qing Plague detoxification，Xuanfeng Fever "Governance Law，Highlights of the group，During the development of the "SARS" period, the first to enter the drug review through the national green channel，In the early stage of the treatment of popular colds and anti -SARS virus, the national patent new drug new medicine connecting flowers clearing capsules。
Experimental studies have confirmed that the drug has an overall regulation advantage: broad -spectrum antiviral，Effective bacteriostatic: H3N2 with type A flu virus H3N2 and multiple influenza and sub -influenza、SARS、avian influenza、Herpes、Aginivirus, etc., all have significant inhibitory effects，At the same time, it can inhibit Golden Polycinius、Pneumococcus、Bacillus Bacteria, etc.; Obvious heating、Anti -inflammatory，Quickly relieve symptoms: Improve the inflammatory response caused by the pathogen to the body，Cough and phlegm，Relieve symptoms。Regulate immune，Enhance My stake betting appstake sports betting appthe body's disease resistance rehabilitation ability: enhance cell and body fluid immune function。Acute toxicity test and long -term toxic test results confirmed the safety of the use of medicine。
Help type Ⅱ diabetic drug development
The second prize of the National Science and Technology Progress Award "Liver, spleen, kidney and kidney -treating law syndrome differentiation treatment of type II diabetes clinical research" was from Beijing University of Traditional Chinese Medicine、Graduate School of Chinese Academy of Chinese Medicine、Guang'anmen Hospital of Chinese Academy of Traditional Chinese Medicine、Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine、Dongfang Hospital of Beijing University of Traditional Chinese Medicine、Beijing Century Temple Hospital Completed。Mainly complete artificial people for Gao Sihua、Gong Yanbing、Ni Qing et al.。
Reasons for winning: This method is guided by the concept of combining traditional Chinese and Western medicine，Combination of disease card，Provides new ideas for the prevention and treatment of type II diabetes，Put forward a new point of view and effective diabetes treatment of diabetes and dialectical treatment，It is important for improving the prevention and treatment of diabetes，It provides an important reference for the research and development of the treatment of drugs in type II diabetes series。
Chinese medicine thinks，Diabetes (the category of Chinese medicine eliminates thirsty disease) and liver、spleen、Cancer of the three dirt in the kidney。This study explores the efficacy and scientificity of type II diabetes in the treatment of type II diabetes。Research Multi -Center collected 265 cases of type II diabetic cases，Syllarsia (165 cases)、Fang 2 (43 cases)、57 cases (57 cases) Add subtraction。Results showing that hypoglycemic thirst 1 square、2 party、3 parties to reduce the total effective rate of lowering blood glucose is 72.03%, respectively、64.10%、74.36%; the total effective rate of blood sugar after meals is 59.69%、62.86%、61.54%。The total effective rate of improving the symptoms of Chinese medicine is 94.9%, respectively、90.57%、91.49%，It has statistically significance，and non -toxic side reaction，Safe and reliable。Research proof，The series of prescriptions of hepatic and spleen and kidneys have exact clinical efficacy，The viewpoint of diabetes through the angle of the liver, spleen, kidney and kidney is correct and scientific。
Traditional Chinese and Western Medicine Integrated Treatment Treatment
The "New Anti -Socuer Sauce Action target and its clinical application" project that won the second prize of the National Science and Technology Progress Award is completed by the Second Military Medical University of the People's Liberation Army。The main complete person is Lingchangquan、Li Min、Feng Yinglu, etc.。
Reasons for winning: This project under the guidance of Chinese medicine theory，For 15 consecutive years with glucocorticoid receptor (GR) as the key observation indicator，From the classic prescriptions of traditional Chinese medicine to single -flavored Chinese medicine to the Chinese medicine composition，Step by step by step out an effective component that can adjust the GR -ginseng saponin，and apply it to clinical，It plays the role of "increased efficiency and reduction" of glucocorticoid (GC)。
This project is based on animal experiments and clinical test results，It proposed "GR reduction is yin deficiency、One of the common pathological foundations of Yang deficiency syndrome "academic perspective，Drugs that can regulate GR (ginsenoside)，and in -depth research on the mechanism of increasing ginseng saponin -elevated GR。Provides a simple simplicity for patients with GC treatment clinically、Effective combined treatment plan，That is conventional GC treatment，Ginseng total saponin 100mg/d。
Chinese medicine formula granules industrialization to a new level
The "Key Technology Research and Application of Industrialization and Application of the Industrialization of Chinese Medicine Formula in Science and Technology Progress Award" project by the National Science and Technology Progress Award "、Jiangyin Tianjiang Pharmaceutical Co., Ltd.、Guangdong Party Pharmaceutical Co., Ltd. completed。Mainly complete artificial Tu Yao Sheng、Zhou Jialin、Tan Dengping equal。
Reasons for winning: After more than ten years of systematic research，Completed with plant medicine、Animal medicine、A total of 723 kinds of single -flavored Chinese medicine extraction、Concentration、Research on spray drying and granular technology，technical problems in the preparation process and quality control better。
The project formulates 723 types of traditional Chinese medicine formula particles、Quality Control Standard，Among them, the characteristic fingerprint diagram of 564 species of 564 species，For 723 varieties、More than 3,000 batches of products conducted quality stability inspections and equivalent comparative complaints with tablets，Completion of the comparative comparison research of ten compound frying and frying of Xiaoyao San、Research on the comparison observation of nearly 1,000 clinical efficacy comparison observation stake online sports bettingresearch，At the same time, My stake betting appa new process for more than 300 varieties was performed、New equipment、Experimental research on new technologies and new accessories。
This project provides a scientific basis and referenceable examples for the unified preparation process and quality standards of Chinese medicine formula particles for relevant national departments，Industrialization of the formula particles of traditional Chinese medicine、Standardization and standardization lays a solid technical foundation。
For the clinical "good medicine" service
The "Clinical Chinese Medicine and Quality Evaluation Model and Method" project that won the second prize of the National Science and Technology Progress Award of Science and Technology "、Wuhan University Complete。Mainly complete people Xiao Xiaohe、Zhao Yanling、King Beber, etc.。
Reasons for winning: The project has established a Chinese medicine and quality evaluation model and method that is in line with the characteristics of traditional Chinese medicine and has original ideas，To achieve the "quality standard of Chinese medicine is closer to clinical，Effective standards are more scientific and scientific "and Chinese medicine-quality-effect-effects-use integrated vision，Scientific improvement and reasonable medication level、Ensure that clinical safety and effectiveness provides new solutions。The key technologies developed include: Chinese medicine cold -thermal recognition technology based on thermal dynamic characteristics; Chinese medicine quality evaluation and control technology based on biological testing; Technology; "toxic" Chinese medicine in the "toxic" Chinese medicine based on the thoughts of "no reason" -Time-effect (toxic) relationship and safety treatment window recognition technology; PK-PD-based traditional Chinese medicine taking method reasonable evaluation technology。Provide technical support and reference for the coordinated development of the upper and lower reaches of the Chinese medicine technology industry for the clinical "good medicine" and the traditional Chinese medicine industry。
Detoxification and removing stasis and nourishing yin method challenge lupus erythematosus
The second prize of the National Science and Technology Progress Award "Establishing and Application of the Efficiency and Remix of Systemic Lupus Eryseng Eryseng Eryseng Eorcycles from Poison and stasis" project，from Zhejiang University of Traditional Chinese Medicine、Guang'anmen Hospital of Chinese Academy of Traditional Chinese Medicine、Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine、The Second Hospital of Affiliated to Zhejiang University Medical College、The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine、Completion of Zhejiang University。Mainly complete people as Fan Yongsheng、Wen Chengping、Jiang Quan, etc.。
Reasons for winning: Systemic lupus erythematosus is a typical refractory rheumatoid disease，At present, the most commonly used clinical treatment is still glucocorticoids and immunosuppressants，Although there is a certain effect，But long -term or large doses of application is prone to hypertension、Hyperipipipipipiperant with high blood lipid、A series of side effects or complications such as osteoporosis and secondary infection。Clinical verification，A series of side effects or complications such as osteoporosis and secondary infection，Can obviously control the condition，Preventive recurrence，Can improve the body's immune function，Significant effects。
Successful examples of modernization of Chinese patent medicine
The "Salviasis Polyphenolic acid and its powder needle" project that won the second prize of the National Technology Invention Award was jointly completed by the Shanghai Academy of Sciences Shanghai Pharmaceutical Institute and Shanghai Green Valley Pharmaceutical Co., Ltd.，Mainly complete people as Xuanli River、Wang Yiping、Xu Yaming, etc.。
Reasons for winning: from 1992，The clinical efficacy of the Chinese Academy of Sciences Shanghai Pharmaceutical Institute is unstable for the clinical efficacy of Danshen and its compound preparations、Adverse reactions often occur problems.，Discovering the water -soluble effective ingredients of Salva is mainly magnesium of Salviane and its homogeneous objects。Discovery through active screening and pharmacological research，Salva Magneste Pharmaceuticals The strongest effect。On the basis of this, it innovatively proposed the use of magnesium ginseng acetate as a quality control standard，Developed stir -up polyphenolic acid powder pins。Shanghai Drugs uses patented technology，Full of enrichment effective parts，Use fingerprint map technology at the same time，For medicinal materials、The quality of the raw drugs and preparations is comprehensively controlled，This ensures the efficiency of Salviac Polyphenol Acid Powder Plurgratous Products、Safety and quality stability、controllable。It overcomes the shortcomings of existing Danshen injection，It has important significance and value in clinical applications，It is an important result obtained by the modernization of traditional Chinese medicine in my country in recent years，Provides a successful example for the modernization of Chinese medicines。
Research on the Research on Molecular Mechanism of Authentic Medicine
The "Research and Application and Application and Application of Research and Application of the National Science and Technology Progress Award for Science and Technology Progress Award"、Institute of Medicinal and Plant Research, Chinese Academy of Medical Sciences、Shandong Analysis and Test Center、Tianjin University Complete。Mainly complete people Huang Luqi、Hu Shilin、Xiao Bagan, etc.。
Reasons for winning: This project takes "authentic formation = genetic mechanism+environmental mechanism" as the general outline，Choose more than ten types of real estate areas to be clear、Typical land medicinal materials commonly used in the community，Using phenotype characteristic mutations as the core，Use modern analysis technology、Molecular biology technology、Space Information Analysis Technology，and multiple statistics、Chemical measurement and other methods，Research authentic and non -land medicinal materials in chemical composition and content、Genetic background、Differences in environmental factor，and the correlation between the three; extract the characteristics of the surface of the ground medicinal material，Clarify its genetic and environmental mechanisms，Further comprehensive analytical scientific connotation，The theory of proposed the formation of local medicinal materials，and verify and apply through control experiments in combination with production practice。At the same time，Analysis of the intellectual property attributes of the medicinal materials，Putting the strategy of proposing the protection of the local medicinal materials。
Reveal the scientific utilization value of Chinese medicine resources
The stake betting appstake online sports betting"Establishment and Application of the Chinese Medicine Resources Chemistry Research System and its application" project that has won the second prize of the National Science and Technology Progress Award of Science and Technology "、Jiangsu Kangyuan Pharmaceutical Co., Ltd.、Jiangsu Provincial Institute of Traditional Chinese Medicine、Gansu Yigui Chinese Medicinal Material Technology Co., Ltd. Completed。Mainly complete people as Duan Jinyu、Xiao Wei、Qian Shihui, etc.。
Reasons for winning: Chinese medicine resource chemistry is a branch discipline for Chinese medicine resources，Based on traditional Chinese medicine resources with traditional medicinal effects and research objects，Based on the development and utilization of resources，Use natural product chemistry、Technology and methods of analyzing chemistry and efficacy evaluation，Reveal Chinese medicine resources (type、Class group) Multiple ways、Multi -layered scientific utilization value。This project follows the subject system and basic argument of natural resources，From the availability and multi -purpose departure of resources，Study the type of chemical composition in natural resources、Quality、Quantity、Time、Space and other basic attributes and their changes。Discussion on the research ideas and methods of the chemistry research of traditional Chinese medicine，Research system establishment and its application，and analyzed the research and comprehensive development and utilization research of Chinese medicine resources in the research instance
The status quo.
Forms a Chinese medicine clinical evidence -based evaluation mode
The clinical trial of the "Qi Shenyi Qi Di Pills for Condition of Myocardial infarction" by the second prize of the National Science and Technology Progress Award "、Chinese Academy of Traditional Chinese Medicine、Peking University First Hospital、Xiyuan Hospital of China Academy of Traditional Chinese Medicine、Tianjin Task Pharmaceutical Co., Ltd.。Mainly complete people as Zhang Boli、Shang Hongcai、Yao Chen, etc.。
Reasons for winning: This is a large -scale Chinese medicine with independent intellectual property rights、Multi -center random control clinical trial，Established and improved the research and evaluation mode of traditional Chinese medicine evidence -based research、Methods and key technologies，Established a randomization of the center、Data Management Electronic and other advanced methods and technology of large -scale clinical research platforms，Form a series of standard operation procedures，Is a example of traditional Chinese medicine evidence -based medical research。
This project is in 16 sub -centers nationwide、84 Chinese and Western Hospitals are carried out at the same time。After 5 years of hard work，A total of 3508 cases of qualified cases，Average follow -up 37. January，Data analysis results indicate，The incidence of the test group and the control group at the complex end event rate、The incidence of cardiovascular death incidence、Non -Deathful Reconstruction Instation Rate、There is no statistical difference between the incidence of non -dead strokes in the incidence of stroke，Reminder that Qi Shen Yilian Pills and Aspirin are equivalent to myocardial infarction secondary prevention effects;、Seattle's Angina pectoris meter and other minor efficiency indicators have no statistical differences in both groups，Reminder that Qi Shen Yishi Pills and enteric Avelin are equivalent to the quality of life after improving myocardial infarction，and compared with the enterico aspirin，Qi Yinyi Drip Pill Safety is particularly good。
Improve the competitiveness of the participation industry in my country
The second prize of the National Science and Technology Progress Award "New Variety Selection and Standardized Cultivation and Series Product Development" project is by Jilin Agricultural University、Institute of Specialty Research Institute of the Chinese Academy of Agricultural Sciences、Correction Pharmaceutical Group、Jilin Aodong Pharmaceutical Group Co., Ltd. completed。Mainly complete people Zhang Lianxue、Yang Limin、Feng family, etc.。
Reasons for winning: This project is divided into people to participate in standardized planting、Analysis of Ginseng Gene sequence and function analysis、Establishment of Ginseng Quality Standards and Fingerprints、Ginseng extraction technology and basic research of drugs、Topics such as the development of people's ginseng -related products。This project gives full play to the advantages of multi -disciplinary joint research，Focus on building basic research -application research -base construction -new drug research and development of innovative value chain，Get a series of innovative results，improved the quality and output of ginseng in my country，Promoting the competitiveness of the ginseng industry。
Reduce the medical cost of the intervertebral disk degeneration disease
The "Basic Research and Clinical Application of Basic Research and Clinical Application for the Treatment of Intervertebral Stake Sports BettingDisposity Diseases for the Treatment of Intervertebral stake sports betting appDisposter Diseases" project of the second prize of the National Science and Technology Progress Award. "、Shanghai Huangpu District Central Hospital、Shanghai Hyundai Chinese Medicine Co., Ltd. completed。Mainly complete people for Wang Yongjun、Shi Qi、Shiyangshan, etc.。
Reasons for winning: This project has made major breakthroughs in the technical and efficacy mechanism of traditional Chinese medicine for the treatment of cervical and lumbar spondylus disease，Form three innovative points。First, the principle of clinical guidance of "reconciling qi and blood" was formed，Established a "disease syndrome combination、Tyromics Theory "Clinical Standardization Plan。Second, the biological research platform of cervical lumbar spondylosis mode was established，revealed the early intervertebral disconnection、Middle、Late "Three changes" rules，clarifying the efficacy mechanism of the delay of the delay of the intervertebral disc.。Third, it formed "Plate source neck and low back pain"、"vertebrae osteophytes are derived from cartilage end board"、Original academic insights such as "Restoration of Spinal Balance" and the role of the role of nourishing qi and stasis。Achievements are widely promoted at home and abroad，reduced medical costs，Reflecting the value of Chinese medicine in the international academic circles。
Metabolic syndrome overall treatment effect is good
The "Chinese Medicine Cognition and Overall Treatment" project of the second prize of the National Science and Technology Progress Award of Science and Technology Progress Award is the Guang'anmen Hospital of the Chinese Academy of Chinese Medical Sciences、Tianjin Tashem Group Co., Ltd. completed。Mainly complete people as Xiaolin、Lian Fengmei、Zhu Yonghong, etc.。
Reasons for winning: This study lasted more than ten years，The first system proposes the theory of the ointment of metabolic syndrome (MS)，Filled the cause of Chinese medicine to MS、Pathopathery、Certificate of Certificate of Certificate, etc., created a mathematical model of the "Nei Jing" type 3 obesity，Provides new ways for MS's risk forecast。MS series governance method was established under the guidance of the theory of turbidity，Based on the Big Huanghuanglian Xiexin Decoction, a series of squares，The first clinical study of Chinese medicine intervention MS is carried out; confirmed that simple Chinese medicine compound treatment of different components MS，Can significantly reduce weight、Reduce waist circumference，Reduce blood glucose、Blood pressure，Improve insulin resistance, etc.，It has an overall treatment effect; compares with similar research with domestic and foreign homes，Breakthroughs in clinical efficacy; the main line with improving insulin resistance，From multiple ways，Explained the scientific connotation of the overall treatment of MS for Chinese medicine compound。Research results have been included in the relevant industry standards and national standard drafts。Relevant prescriptions are applied at more than 80 hospitals at home and abroad，Its theory is in Canada、South Africa、Japan、India and other more than 10 countries have been recognized，Training more than 500 specialists，Cumulative economic benefits of more than 100 million yuan。
The advantages of the prevention and treatment of traditional Chinese medicine are obvious
The "Chinese Medicine Lianhua Qing Plague Research" project, which won the second prize of the National Science and Technology Progress Award, was based on Shijiazhuang Yiling Pharmaceutical Co., Ltd.、Beijing You'an Hospital Affiliated to Capital Medical University Completed。Mainly complete people for Jia Zhenhua、Wu Yiling、Guo Shuanggeng, etc.。
Reasons for winning: This study is a more mature and complete Chinese medicine application research。First use the concept of the vein space position of the "three -dimensional stereo network system" in China in China，Discuss the characteristics of the pathogenesis of external temperature and fever and plague from Yangluo to the meridian stage, and the transmission law that is easy to pass into the internal organs and yin，Put forward the "active intervention" treatment concept:，Double solution in the table;，Tripping the disease; overall adjustment，Multi -target treatment，Develop "Qing Plague detoxification，Xuanfeng Fever "Governance Law，Highlights of the group，During the development of the "SARS" period, the first to enter the drug review through the national green channel，In the early stage of the treatment of popular colds and anti -SARS virus, the national patent new drug new medicine connecting flowers clearing capsules。
Experimental studies have confirmed that the drug has an overall regulation advantage: broad -spectrum antiviral，Effective bacteriostatic: H3N2 with type A flu virus H3N2 and multiple influenza and sub -influenza、SARS、avian influenza、Herpes、Aginivirus, etc., all have significant inhibitory effects，At the same time, it can inhibit Golden Polycinius、Pneumococcus、Bacillus Bacteria, etc.; Obvious heating、Anti -inflammatory，Quickly relieve symptoms: Improve the inflammatory response caused by the pathogen to the body，Cough and phlegm，Relieve symptoms。Regulate immune，Enhance My stake betting appstake sports betting appthe body's disease resistance rehabilitation ability: enhance cell and body fluid immune function。Acute toxicity test and long -term toxic test results confirmed the safety of the use of medicine。
Help type Ⅱ diabetic drug development
The second prize of the National Science and Technology Progress Award "Liver, spleen, kidney and kidney -treating law syndrome differentiation treatment of type II diabetes clinical research" was from Beijing University of Traditional Chinese Medicine、Graduate School of Chinese Academy of Chinese Medicine、Guang'anmen Hospital of Chinese Academy of Traditional Chinese Medicine、Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine、Dongfang Hospital of Beijing University of Traditional Chinese Medicine、Beijing Century Temple Hospital Completed。Mainly complete artificial people for Gao Sihua、Gong Yanbing、Ni Qing et al.。
Reasons for winning: This method is guided by the concept of combining traditional Chinese and Western medicine，Combination of disease card，Provides new ideas for the prevention and treatment of type II diabetes，Put forward a new point of view and effective diabetes treatment of diabetes and dialectical treatment，It is important for improving the prevention and treatment of diabetes，It provides an important reference for the research and development of the treatment of drugs in type II diabetes series。
Chinese medicine thinks，Diabetes (the category of Chinese medicine eliminates thirsty disease) and liver、spleen、Cancer of the three dirt in the kidney。This study explores the efficacy and scientificity of type II diabetes in the treatment of type II diabetes。Research Multi -Center collected 265 cases of type II diabetic cases，Syllarsia (165 cases)、Fang 2 (43 cases)、57 cases (57 cases) Add subtraction。Results showing that hypoglycemic thirst 1 square、2 party、3 parties to reduce the total effective rate of lowering blood glucose is 72.03%, respectively、64.10%、74.36%; the total effective rate of blood sugar after meals is 59.69%、62.86%、61.54%。The total effective rate of improving the symptoms of Chinese medicine is 94.9%, respectively、90.57%、91.49%，It has statistically significance，and non -toxic side reaction，Safe and reliable。Research proof，The series of prescriptions of hepatic and spleen and kidneys have exact clinical efficacy，The viewpoint of diabetes through the angle of the liver, spleen, kidney and kidney is correct and scientific。
Traditional Chinese and Western Medicine Integrated Treatment Treatment
The "New Anti -Socuer Sauce Action target and its clinical application" project that won the second prize of the National Science and Technology Progress Award is completed by the Second Military Medical University of the People's Liberation Army。The main complete person is Lingchangquan、Li Min、Feng Yinglu, etc.。
Reasons for winning: This project under the guidance of Chinese medicine theory，For 15 consecutive years with glucocorticoid receptor (GR) as the key observation indicator，From the classic prescriptions of traditional Chinese medicine to single -flavored Chinese medicine to the Chinese medicine composition，Step by step by step out an effective component that can adjust the GR -ginseng saponin，and apply it to clinical，It plays the role of "increased efficiency and reduction" of glucocorticoid (GC)。
This project is based on animal experiments and clinical test results，It proposed "GR reduction is yin deficiency、One of the common pathological foundations of Yang deficiency syndrome "academic perspective，Drugs that can regulate GR (ginsenoside)，and in -depth research on the mechanism of increasing ginseng saponin -elevated GR。Provides a simple simplicity for patients with GC treatment clinically、Effective combined treatment plan，That is conventional GC treatment，Ginseng total saponin 100mg/d。
Chinese medicine formula granules industrialization to a new level
The "Key Technology Research and Application of Industrialization and Application of the Industrialization of Chinese Medicine Formula in Science and Technology Progress Award" project by the National Science and Technology Progress Award "、Jiangyin Tianjiang Pharmaceutical Co., Ltd.、Guangdong Party Pharmaceutical Co., Ltd. completed。Mainly complete artificial Tu Yao Sheng、Zhou Jialin、Tan Dengping equal。
Reasons for winning: After more than ten years of systematic research，Completed with plant medicine、Animal medicine、A total of 723 kinds of single -flavored Chinese medicine extraction、Concentration、Research on spray drying and granular technology，technical problems in the preparation process and quality control better。
The project formulates 723 types of traditional Chinese medicine formula particles、Quality Control Standard，Among them, the characteristic fingerprint diagram of 564 species of 564 species，For 723 varieties、More than 3,000 batches of products conducted quality stability inspections and equivalent comparative complaints with tablets，Completion of the comparative comparison research of ten compound frying and frying of Xiaoyao San、Research on the comparison observation of nearly 1,000 clinical efficacy comparison observation stake online sports bettingresearch，At the same time, My stake betting appa new process for more than 300 varieties was performed、New equipment、Experimental research on new technologies and new accessories。
This project provides a scientific basis and referenceable examples for the unified preparation process and quality standards of Chinese medicine formula particles for relevant national departments，Industrialization of the formula particles of traditional Chinese medicine、Standardization and standardization lays a solid technical foundation。
For the clinical "good medicine" service
The "Clinical Chinese Medicine and Quality Evaluation Model and Method" project that won the second prize of the National Science and Technology Progress Award of Science and Technology "、Wuhan University Complete。Mainly complete people Xiao Xiaohe、Zhao Yanling、King Beber, etc.。
Reasons for winning: The project has established a Chinese medicine and quality evaluation model and method that is in line with the characteristics of traditional Chinese medicine and has original ideas，To achieve the "quality standard of Chinese medicine is closer to clinical，Effective standards are more scientific and scientific "and Chinese medicine-quality-effect-effects-use integrated vision，Scientific improvement and reasonable medication level、Ensure that clinical safety and effectiveness provides new solutions。The key technologies developed include: Chinese medicine cold -thermal recognition technology based on thermal dynamic characteristics; Chinese medicine quality evaluation and control technology based on biological testing; Technology; "toxic" Chinese medicine in the "toxic" Chinese medicine based on the thoughts of "no reason" -Time-effect (toxic) relationship and safety treatment window recognition technology; PK-PD-based traditional Chinese medicine taking method reasonable evaluation technology。Provide technical support and reference for the coordinated development of the upper and lower reaches of the Chinese medicine technology industry for the clinical "good medicine" and the traditional Chinese medicine industry。
Detoxification and removing stasis and nourishing yin method challenge lupus erythematosus
The second prize of the National Science and Technology Progress Award "Establishing and Application of the Efficiency and Remix of Systemic Lupus Eryseng Eryseng Eryseng Eorcycles from Poison and stasis" project，from Zhejiang University of Traditional Chinese Medicine、Guang'anmen Hospital of Chinese Academy of Traditional Chinese Medicine、Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine、The Second Hospital of Affiliated to Zhejiang University Medical College、The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine、Completion of Zhejiang University。Mainly complete people as Fan Yongsheng、Wen Chengping、Jiang Quan, etc.。
Reasons for winning: Systemic lupus erythematosus is a typical refractory rheumatoid disease，At present, the most commonly used clinical treatment is still glucocorticoids and immunosuppressants，Although there is a certain effect，But long -term or large doses of application is prone to hypertension、Hyperipipipipipiperant with high blood lipid、A series of side effects or complications such as osteoporosis and secondary infection。Clinical verification，A series of side effects or complications such as osteoporosis and secondary infection，Can obviously control the condition，Preventive recurrence，Can improve the body's immune function，Significant effects。
