[my country ’s existing pharmaceutical manufacturers 4867，Among them, 75%are small companies with annual sales of less than 50 million yuan。]

 

  [You can see that there are 169390 domestic drug batch numbers on the website of the State Food and Drug Administration，There are 4335 imported drug batch numbers。But these batch numbers occupying the digital sequence，Not every one is playing a role。]

 

  [About 80%of Chinese medicines sold in hospitals，More than 400,000 retail pharmacies，Sales account for 22.4%of all medicines。]

 

  A lot of & ldquo; Qualified invalid pills & rdquo; fill the market，Small enterprise standards with a proportion of 75%、Low crafts，There are hidden dangers of quality and safety，A lot of & ldquo; Zombie & rdquo; batch number exists，The State Administration of Food and Drug Administration lit a sharp sword，For the bloated pharmaceutical market，Promoting medication safety。

 

  Bi Jingquan, Director of the State Food and Drug Administration, in 2016 & ldquo; National Safety Medicine Month & RDQUO;，& ldquo; The regulatory authorities must strictly put the & lsquo; listing & rsquo;。The basic principle of the listing of drugs is safe and effective，If the medicine is invalid，It will be treated with misunderstanding，Waste resources，This is also the biggest unsafe。& rdquo;

 

  Buried & ldquo; Zombie batch number & rdquo;

 

  4867 existing pharmaceutical manufacturers in my country，Among them, 75%are small companies with annual sales of less than 50 million yuan。Drug approval number exceeds 187,000，A large part is approved by the local area before 1997，After turning to My stake betting appstake online sports bettingthe country's recognized Chinese medicine quasi -name，Standards and production processes are relatively low，There is a certain quality safety hazard。In addition，Eximmonds, although chemical composition is the same as the original medicine，but lack of clinical verification，Some biological equivalent has not been verified，So there will be so -called & ldquo; Qualified invalid medicine & rdquo;。

 

  The State Food and Drug Administration announced in May last year "Medicine、Registration and charge standards for medical device products "and" Detailed Rules for Implementation of Drug Registration and Fees (Trial) "、"Implementation Rules for Registration and Fees for Medical Device Products (Trial)"，Adjusted drug registration charging standards，Formulated a new charging standard for medical device，Adjusted domestic new drug registration application charging standard is 624,000 yuan，Imported drug replacement required 227,200 yuan，Domestic drugs have a five -year permit change fee by provincial price、Formulated by the financial department。

 

  & ldquo; The past batch number was lifelong system，Not charging for a certificate，A piece of paper can change hundreds of batch numbers in your hand，So many companies hold a lot of batch number，Some even conduct batch numbers buying and selling。Now the country has to approve the price increase，Certificate changes also requires charges，For example, it takes 200,000 to change a certificate，The company will select its own batch number。& rdquo; The president of a pharmaceutical company said。

 

  Dested，Although you can see that there are 169390 domestic drug batch numbers on the website of the State Food and Drug Administration，There are 4335 imported drug batch numbers。But these batch numbers occupying the digital sequence，Not every one is playing a role。For example, 11 Gaoxin tablets batch number，Only two are playing the role of saving people to treat people，Other batch numbers are & ldquo; Dormation & rdquo;。

 

  If the certificate change fee cannot be buried all of those zombies batch number，The consistency evaluation of generic drugs will make these zombie batch thoroughly die。The General Office of the State Council issued the "Opinions on the Evaluation of the Consistency of the Quality and Effects of Photics" (hereinafter referred to as "Opinions")，Consistency evaluation of the quality and efficacy of the listed generic drugs is fully expanded，Overdue incomplete，Never registered。

 

  This is another barrier of the State Food and stake sports betting appstake betting appDrug Administration on the weight loss of pharmaceutical companies，This pass not only enhances the effectiveness of the medicine，It will also reduce batch number，Even pharmaceutical companies that are unable to close from here。

 

  The State Food and Drug Administration issued the "Announcement on the Inspection of Self -examination of the Pharmaceutical Clinical Test Data (2015 No. 117)，Requires from the date of the announcement，All drug registration applicants who have declared and for review at the State Administration，All must be in accordance with the relevant requirements of the "Management of the Quality Management of Drug Clinical Test"，Comparison clinical trial scheme，Self -examination of clinical trials of drug registration applications for production or imported production or imports，Make sure the clinical trial data is true、Reliable，Related evidence is stored complete。

 

  & ldquo; In the past 5,000 yuan, you can buy a pharmaceutical clinical trial data，It will be difficult to operate like this now。& rdquo; An person who has been engaged in drug research and development for a long time said。& ldquo;，It should be strict，The clinical is too messy，Prices soaring，Corporate fraud，I estimate that more than 50%of them are fake。There are many ways to counterfeit，The level of high level cannot be found。& rdquo;

 

  The four major safety medicines outside the supervision

 

  Bi Jingquan said at the meeting，Safety safety safety is both the drug regulatory department、Production Enterprise、Medical Institution、Responsibility for retail pharmacies，It also needs public、Media to participate together。

 

  In addition to supervision this level，From production，Go to the medical use unit，Go to retail pharmacy，Then to patient，The threat of drug safety exists everywhere。

 

  Academician of the Chinese Academy of Engineering、The chairman of the Chinese Pharmaceutical Society Sang Guowei believes，Drug safety issues，reflected in two aspects。First, there must be medicines that meet the clinical needs，At present, 90%of the diseases of more than 4,500 diseases around the world are not cured or have no effective treatment drugs，Extrudicated good medicine for the common people，Especially major diseases such as malignant tumors、The treatment of diabetes such as diabetes with a significant increase in prevalence，Now mainly uses imitation，my country's pharmaceutical development urgently needs innovation drive。Followed by these stake sports betting appStake Sports Bettingstake betting appdrugs, it must be safe when used，Including production、Pay attention to safety during the process of circulation and use，enables the drug to reach the ideal risk-benefit ratio。

 

  & ldquo; The production and operation enterprise must strictly control the quality，Enterprise is the first person in charge of drug safety，We must strictly follow the production of drug production quality management specifications，Strictly abide by the formula and process approved by the regulatory department，Any craftsmanship that may affect the safety of drugs、Formula change，It must be declared in time。To reform the drug circulation system，Encourage direct transactions of pharmaceutical companies and medical institutions and retail pharmacies，Development distribution and distribution、Chain Operation，Reincarnation for prohibiting the resale of not being responsible for drug safety、illegal acts and other illegal behaviors。& rdquo; Bi Jingquan said。

 

  Even if there is a safe medicine，Any small factors in the use link will bring unsafe people to the common people。Current，About 80%of Chinese medicines sell in hospitals，More than 400,000 retail pharmacies，Sales account for 22.4%of all medicines。2015，my country's retail pharmacy sales totaling 311.1 billion yuan，Sales of medical institutions for a total of 1075.3 billion yuan，The proportion is 77.6%。

 

  & ldquo; Medical institutions must strictly control the prescription，Is the medicine safe and effective，Clinicians have the most right to speak。To encourage doctors to actively participate in drug research and development、Pharmaceutical listing review、Evaluation after the pharmaceutical listing。Clinical medication should follow safety、Effective、Principles of reasonable medication in the economy，Respect the patient's right to know the use of drugs。& rdquo; Bi Jingquan said。

 

  According to the requirements of "Pharmaceutical Safety & Ldquo; Twelve Five -Year Plan" issued by the State Council in 2012，The legal representative or person in charge of the drug operating enterprise must have the qualifications of a practicing pharmacist; retail pharmacies must be equipped with a practicing pharmacist，Responsible for prescription review，Guide patients with reasonable medication。& ldquo; Current，The number of registered applicants for practicing pharmacists in my country has exceeded 320,000，Among them, there are nearly stake betting appMy stake betting app280,000 practitioners in retail pharmacies，Still unable to satisfy the need。To improve the status of a practicing pharmacist，Increases occupational attraction and sense of honor，Expand occupational development space，Encourage more professional and technical personnel to join the practice pharmacist team。& rdquo; Bi Jingquan said。

 

  At the same time in the consumer link，It should be strengthened for safety medication。Bi Jingquan thinks，Consumers are the last link of the entire cycle of the medicine，It is also the core subject that ultimately reflects the efficacy and bearing risks。Consumers must strengthen self -protection awareness，See a doctor when you are sick，Medicine to follow the doctor's advice。Relevant parties should strengthen all kinds of medicines、Health food、Food instructions、Tags and Name Management，Strengthen drug advertising management，Forbidden exaggeration to propaganda、false publicity，It is forbidden to any misleading words to consumers、Word，Effectively protect the majority of consumers, especially the elderly, is not affected by various false propaganda。